Randomized Controlled Trial: Topical CBD Treatment Provides Relief for Arthritis Patients

Charlottesville, Virginia: Administration of a topical formula containing hemp-derived CBD is associated with significant improvements in patients with basal joint arthritis of the thumb, according to data from randomized clinical trials published in the hand surgery journal.

Researchers at the University of Virginia School of Medicine evaluated twice-daily application of 1 mL of topical CBD (6.2 mg/mL) with shea butter versus a placebo in 18 arthritis patients symptomatic basal thumb.

The investigators reported: “Cannabidiol treatment resulted in improvements from baseline in patient-reported outcome measures, including pain on the visual analogue scale; Arm, shoulder and hand disabilities; and single-assessment numerical assessment scores, relative to the control group during the study period. »

They concluded, “In this single-center randomized controlled trial, topical CBD treatment demonstrated significant improvements in pain and disability related to basal arthritis of the thumb with no adverse events.”

The results contrast with those of a 2021 Danish study reporting that oral administration of synthetic CBD did not alleviate pain in patients with hand osteoarthritis.

Data from the Canadian survey published earlier this month in the journal Clinical and experimental rheumatology reported that one in five arthritis patients admitted to using cannabis for therapeutic purposes.

The full text of the study, “A randomized controlled trial of topical cannabidiol for the treatment of basal joint arthritis of the thumb,” appears in the Journal of Hand Surgery. Additional information on cannabis and arthritis is available at NORMAL.

About Antoine L. Cassell

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